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A clinical trial of Actiphage, a promising new diagnostic for tuberculosis infection, has shown for the first time that live bacteria can be detected in the blood of people with incipient TB infection.

Sub-Saharan Africa is devastated by TB disease. Zambia, has a high TB/HIV burden – 59,000 people developed TB in 2020 and 15,000 died. There is a critical need for a non-sputum based rapid test for diagnosing TB disease.

Bacteriophages, viruses that infect and kill bacteria, offer the potential of a powerful tool for detecting and treating mycobacterial infections such as tuberculosis (TB), authors of a review in the journal Microorganisms* have reported.

Of the 10 million individuals who became ill with 'active' TB in 2018, approximately three million were missed by health systems, according to the Centres for Disease Control and Prevention (CDC)

Innovation directed at an unmet market need can stimulate economic development if the value creation is kept within the local economy. The recent pandemic has shown the huge value of diagnostics and tuberculosis (TB), for which there are currently few...

PBD Biotech, developers of a phage-based diagnostic for tuberculosis, is moving to the next stage of its development. It is appointing Jane Theaker, of precision medicine company Kinomica, as the new CEO and bringing Commercial Director, Jonnie Yewdall, into a...

Albert’s research, ‘Use of 2, 3, 5-Triphenyltetrazolium chloride (TTC) to assay the kinetics of phage and host interactions’, is sponsored by PBD Biotech through the BBSRC CASE initiative, and was co-authored by fellow Nottingham student Philip J. Hill and PBD...

You can view press releases from PBD Biotech in pdf format from this page.

Worldwide a quarter of a million children die of tuberculosis (TB) each year, early diagnosis would help to save their lives but most are unable to produce the sample of mucus that is needed for the current test.

Tuberculosis (TB) is the leading cause of death from an infectious disease. Although a quarter of the world’s population is thought to carry latent TB, it carries a risk of progressing to the active form of TB in around 10%...

Tuberculosis (TB) is the leading cause of death from an infectious disease. Although a quarter of the world’s population is thought to carry latent TB, it only progresses to active disease in around 10% of those infected. The reasons for...

After growing PBD Biotech from start-up to international player in just three years, Dr Berwyn Clarke has decided to retire as CEO to make time for other business interests. He will remain on the diagnostics company’s Board of Directors.