Mycobacteria are responsible for a number of diseases including: Bovine tuberculosis, a chronic, infectious disease caused by Mycobacterium bovis (M.bovis), it can infect humans, livestock, wildlife, and exotic species and Johne's Disease or ParaTB which is a wasting disease in ruminants.
Unlike other technologies, the Actiphage test does not measure an immune response, but specifically detects the DNA extracted from live Mycobacteria present in circulating blood as a marker of disease.
PBD Biotech is currently in the process of verifying the Actiphage test for the detection of Mycobacterium bovis (bovine TB) in cattle blood.
Certification by the World Organisation for Animal Health (WOAH) is required for a bTB diagnostics to become an internationally recognised diagnostic, however, Actiphage can be used as a diagnostic in England and Wales for disease management in areas of chronic disease breakdown.
These restrictions are not in place for Johne's Disease also known as MAP and PBD Biotech is developing a commercial Johne's Disease testing service.
Actiphage for Bovine tuberculosis
Actiphage for Johne's Disease
Actiphage for milk testing
Actiphage is able to detect most other mycobacterial species and has been successfully applied to samples from multiple animal species.
PBD Biotech has proof-of-concept data that the test can be applied to over species, and remains open to collaboration with researchers and regulators across the globe who want to advance the science and understanding of these devastating diseases.
