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At PBD, we partner to develop Actiphage for the acceleration of latent tuberculosis (LTBI) test and treat campaigns and TB drug research through the following: Laboratory-developed tests to support research studies for latent tuberculosis  screening. Companion diagnostic TB drug research...

Actiphage assay workflow steps Quick overview of the Actiphage assay workflow. Actiphage blood collection 2ml blood sample (sodium heparin) is required. Not refrigerated or frozen; shipped at ambient = 10-24C. Processed to the start of phage incubation, within 48 hours...

Actiphage detects mycobacterium tuberculosis in latent TB patients associated with progression to active tuberculosis. Actiphage clinical studies have found: Actiphage provided the first concordant evidence in humans to detect incipient TB in early infection. Actiphage had high correlation of 73%...

Actiphage supports test and treat TB campaigns through: Preventive TB treatment Progression from untreated LTBI to TB disease accounts for approximately 80% of TB cases. Testing and treating people living with TB infection is essential to eliminating TB disease. Preventive...

Role as a biomarker for TB prevention and drug development Actiphage is a detection technology that has been shown to  identify patients at greatest risk of progression to TB disease. Actiphage could potentially be used for a “rule-in” preventive therapy...

Actiphage is a novel bacteriophage-based assay that infects and lyses active Mtb to release bacterial DNA for PCR based detection. It is designed for laboratory TB testing. In clinical studies Actiphage has been shown to have: higher specificity and sensitivity...

On average, 5–10% of people who are infected with TB will develop disease over the course of their lives, creating a driver for TB drug research. Early diagnosis of TB, systematic screening, preventive treatment of persons, and vaccination against TB...

Find out more about diagnosing TB in humans

Find out more about diagnosing TB in humans

Find out more about diagnosing TB in humans

Actiphage provides a highly specific and sensitive assay for the cost-effective detection of mycobacterial disease in blood.

Actiphage offers benefits over tests that rely on an immune response.