Phage Based Diagnostics

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Animal Health

Bovine TB is emotionally and economically devastating. 289,000 cattle have been slaughted in the UK in the last 10 years and compensation cost the tax payer £34m in 2018/19. There must be an alternative to 'test and cull'.

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Bovine tuberculosis is a chronic, infectious disease caused by Mycobacterium bovis (M.bovis), it can infect humans, livestock, wildlife, and exotic species.

Unlike other technologies, the Actiphage test does not measure an immune response, but specifically detects the DNA extracted from live Mycobacteria present in circulating blood as a marker of disease.

PBD Biotech is currently in the process of verifying the Actiphage test for the detection of Mycobacterium bovis (bovine TB) and M. avium subsp paratuberculosis (MAP), (Johne’s disease) in cattle blood.

Certification of Actiphage by the World Organisation for Animal Health (OIE) as an internationally recognised diagnostic for bTB is PBD Biotech’s primary focus for animal health.

However, Actiphage is able to detect most other mycobacterial species and has been successfully applied to samples from multiple animal species.

PBD Biotech has proof-of-concept data that the test can be applied to over 20 species, including humans, and remain open to collaboration with researchers and regulators across the globe who want to advance the science and understanding of these devastating diseases.

Actiphage and bovine TB.

Actiphage and Johne's Disease or MAP

Actiphage and exotic species

To use the Johne's Testing Service for blood or bulk milk do get in touch

If you are interested in using Actiphage for research use the order form or contact us

New testing service for Johne’s Disease/MAP

If you would like to know more about our testing service or to discuss the use of test kits for research do get in touch.

Related content

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Actiphage detects Johne’s disease in vaccinated goat

June 9, 2022
A study presented at ICP 2022 has shown that the blood test Actiphage is able to distinguish between goats that are naturally infected and those vaccinated against Mycobacterium avium subspecies paratuberculosis (MAP), the pathogen that causes Johne’s Disease, supporting the...

Actiphage detects Johne’s disease in vaccinated goat

June 9, 2022
A study presented at ICP 2022 has shown that the blood test Actiphage is able to distinguish between goats that...
Actiphage use as a DIVA test

Actiphage optimised to detect MAP in humans and to support use as ‘DIVA’

June 1, 2022
This is the first time Actiphage has been used to detect MAP in a human blood sample and also to identify a live infection in a vaccinated goat.
Actiphage use as a DIVA test

Actiphage optimised to detect MAP in humans and to support use as ‘DIVA’

June 1, 2022
This is the first time Actiphage has been used to detect MAP in a human blood sample and also to...
bison MAP diagnostic

Actiphage identifies strain of mycobacteria in blood of bison

May 26, 2022
Results presented at ICP (12-16th June) from first study in North American bison, shows capacity of Actiphage to sub-type mycobacteria in blood.
bison MAP diagnostic

Actiphage identifies strain of mycobacteria in blood of bison

May 26, 2022
Results presented at ICP (12-16th June) from first study in North American bison, shows capacity of Actiphage to sub-type mycobacteria...
cow

Why breakthrough human trials of Actiphage are good news for farmers

May 12, 2022
The findings are a real breakthrough for animal diagnosis as it provides clinical evidence that detection of low levels of mycobacteria in the blood is an indication that the animal is infected and has the potential to develop disease.
cow

Why breakthrough human trials of Actiphage are good news for farmers

May 12, 2022
The findings are a real breakthrough for animal diagnosis as it provides clinical evidence that detection of low levels of...
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developers of phage-based diagnostics

Contact Us

PBD Biotech Ltd
Link House, Elm Farm Park,
Great Green, Thurston,
Suffolk IP31 3SH,
United Kingdom

Registered Company Address
Ingenuity Centre,
University of Nottingham,
Innovation Park, Triumph Rd,
Nottingham NG7 2TU,
United Kingdom

T: 01359 231856
info@pbdbio.com

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