Phage Based Diagnostics

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  • Home
  • About
    • About PBD Biotech
    • Industry Awards
    • Management Team
    • International
  • Actiphage
    • About Actiphage
    • Benefits of Actiphage
    • Rapid detection of mycobacterial disease
  • Bovine
    • Bovine TB
    • Johne’s Disease
    • Dairy Industry
  • Latest
    • Articles
    • Events
  • Case Studies
  • Research
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    • Product Order Form
    • Contacting us

Animal Health

Bovine TB is emotionally and economically devastating. 289,000 cattle have been slaughted in the UK in the last 10 years and compensation cost the tax payer £34m in 2018/19. There must be an alternative to 'test and cull'.

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Arden Farms deer

Arden Farms first to test deer for Johne’s Disease using Actiphage

Arden Farms are the first to use the Actiphage® blood test to test their herd of Red Deer for Johne’s...

Mycobacteria are responsible for a number of diseases including: Bovine tuberculosis, a chronic, infectious disease caused by Mycobacterium bovis (M.bovis), it can infect humans, livestock, wildlife, and exotic species and Johne's Disease or ParaTB which is a wasting disease in ruminants.

Unlike other technologies, the Actiphage test does not measure an immune response, but specifically detects the DNA extracted from live Mycobacteria present in circulating blood as a marker of disease.

PBD Biotech is currently in the process of verifying the Actiphage test for the detection of Mycobacterium bovis (bovine TB) in cattle blood.

Certification by the World Organisation for Animal Health (OIE) is required for a bTB diagnostics to become an internationally recognised diagnostic, however, Actiphage can be used as a diagnostic in England and Wales for disease management in areas of chronic disease breakdown.

These restrictions are not in place for Johne's Disease also known as MAP and PBD Biotech has launched a commercial Johne's Disease testing service.

Testing in over 20 species

However, Actiphage is able to detect most other mycobacterial species and has been successfully applied to samples from multiple animal species.

PBD Biotech has proof-of-concept data that the test can be applied to over 20 species, including humans, and remain open to collaboration with researchers and regulators across the globe who want to advance the science and understanding of these devastating diseases.

Read more about the testing for Johne's Disease (ParaTB), MAP and bovine TB

Actiphage and bovine TB.

Actiphage and Johne's Disease or MAP

Actiphage and exotic species

MAP testing for milk quality assurance

To use the Johne's Testing Service for blood or bulk milk do get in touch

If you are interested in using Actiphage for research use the order form or contact us

New testing service for Johne’s Disease/MAP

If you would like to know more about our testing service or to discuss the use of test kits for research do get in touch.

Related content

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See PBD Biotech at The Dairy Show

5 October 2022

See us at The Dairy Show

September 6, 2022
Ensuring consumer confidence in dairy products has never been more vital and we are delighted to have the opportunity to talk about our new blood test and bulk milk test with producers, cheesemakers, dairy companies and others across the industry...
See PBD Biotech at The Dairy Show

5 October 2022

See us at The Dairy Show

September 6, 2022
Ensuring consumer confidence in dairy products has never been more vital and we are delighted to have the opportunity to...

Actiphage detects Johne’s disease in vaccinated goat

June 9, 2022
A study presented at ICP 2022 has shown that the blood test Actiphage is able to distinguish between goats that are naturally infected and those vaccinated against Mycobacterium avium subspecies paratuberculosis (MAP), the pathogen that causes Johne’s Disease, supporting the...

Actiphage detects Johne’s disease in vaccinated goat

June 9, 2022
A study presented at ICP 2022 has shown that the blood test Actiphage is able to distinguish between goats that...
Actiphage use as a DIVA test

Actiphage optimised to detect MAP in humans and to support use as ‘DIVA’

June 1, 2022
This is the first time Actiphage has been used to detect MAP in a human blood sample and also to identify a live infection in a vaccinated goat.
Actiphage use as a DIVA test

Actiphage optimised to detect MAP in humans and to support use as ‘DIVA’

June 1, 2022
This is the first time Actiphage has been used to detect MAP in a human blood sample and also to...
bison MAP diagnostic

Actiphage identifies strain of mycobacteria in blood of bison

May 26, 2022
Results presented at ICP (12-16th June) from first study in North American bison, shows capacity of Actiphage to sub-type mycobacteria in blood.
bison MAP diagnostic

Actiphage identifies strain of mycobacteria in blood of bison

May 26, 2022
Results presented at ICP (12-16th June) from first study in North American bison, shows capacity of Actiphage to sub-type mycobacteria...
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developers of phage-based diagnostics

Contact Us

Registered Company Address
Grosvenor St Paul’s
Grosvenor House
11 St Paul’s Square
Birmingham
B3 1RB
United Kingdom

T: 01359 231856
info@pbdbio.com

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